3D Printed Metastatic Malignant Melanoma

3D Printed Metastatic Malignant Melanoma Clinical History A 65-year old male with presents with pain in his left groin. He has a history of skin melanoma on his left foot treated with surgical resection and radiotherapy. On examination, he is cachexic with a hard, enlarged liver and has a discharging sinus in the left groin surrounded by black nodules. He is admitted and dies from a hospital-acquired pneumonia. Pathology The specimen is the patient’s proximal right femur sawn longitudinally to display the cut surface. The medullary cavity contains many deposits of tumour tissue varying in colour from a pale brown to black. Cancellous bone has been completely destroyed by the larger deposits, which appear dark and measure up to 3 cm in maximum diameter. Elsewhere pale brown tumour infiltrates the marrow cavity diffusely. Cortical bone has been spared, although at the junction of the shaft and neck, medially the cortical bone is discoloured and thickened.