3D Printed Metastatic Melanoma

3D Printed Metastatic Melanoma Clinical HistoryIn the 1970s, a 31-year-old woman presented with severe headache and diplopia on a background of having a pigmented skin lesion (diagnosed as an invasive skin melanoma) removed from her neck 8 months earlier. Clinical examination revealed no abnormality, and following discharge the patient was later re-admitted with persistent vomiting. Her condition deteriorated and she died. PathologyThis specimen demonstrates widespread intracerebral melanoma metastases. The inferior surface is characterised by many elevated dark nodules up to 1.5 cm in diameter. Similar lesions are present on the cut superior surface where it is seen that these secondary melanotic deposits are confined exclusively to the grey matter. The tumour deposits are not encapsulated and are invading the cortex. Some necrosis and haemorrhage is present. Further informationOf all patients who have metastatic disease to the brain, 10% are from skin mel