Anti-Human CCL2 Monoclonal Antibody, Clone:Carlumab

  Anti-Human CCL2 Monoclonal Antibody, Clone: Carlumab Clone: Carlumab                            Catalog#: AB5803 Description: CCL2 is the most well-known CC chemokine. CCL2 has chemotactic activity for monocytes and basophils. It is one of the key chemokines that regulate monocyte / macrophage migration and infiltration. CCL2 plays a role in tumor development. In many types of cancer, CCL2 signaling has a pro-tumor effect. Elevated levels of CCL2 are often associated with disease progression in patients with breast cancer, colorectal cancer, prostate cancer, melanoma, gastric cancer, and ovarian cancer. Overexpression of CCL2 or the presence of genetic variants is associated with increased recruitment of macrophages and poor patient outcomes. Reactivities: Human Target: CCL2 Clone: Carlumab Isotype: Human IgG1(E356D/M358L)-kappa Alternative Name: CNTO 888;chemokine (C-C motif) ligand 2, C-C motif chemokine 2, monocyte chemoattractant protein-1, MCP-1, mo