Anti-Human CD137 Monoclonal Antibody, Clone: Utomilumab

  Anti-Human CD137 Monoclonal Antibody, Clone: Utomilumab Clone: Utomilumab                  Catalog#: AB5242 Description: CD137, also known as 4-1BB, is an inducible co-stimulatory receptor that is a transmembrane glycoprotein and belongs to the tumor necrosis factor receptor (TNFR) family. It is encoded by the gene TNFRSF9.CD137 is primarily expressed on activated CD4+ and CD8+ T cells, natural killer (NK) cells, and constitutively expressed on regulatory T cells. In addition, CD137 is also expressed on activated macrophages, B cells, and dendritic cells. The ligand of CD137 is called CD137 Ligand, which is mainly expressed on activated antigen-presenting cells (APCs), such as dendritic cells (DCs), B cells, monocytes, and phagocytic cells. Reactivities: Human Target: CD137 Clone: Utomilumab Isotype: Human IgG2-Lambda 2 Alternative Name: PF-05082566; PF 05082566; 1417318-27-4; 4-1BB/CD137 antibody; 4-1BB/CD137; CD137 antigen agonists; PF-2566; PF-5082566