Actin, Alpha Skeletal Muscle, Rabbit Protein

Description Actin, Alpha Skeletal Muscle, Rabbit Protein is an ultra-pure Actin protein in the alpha-skeletal muscle isoform, purified from rabbit striated muscle. The purification method used (according to Spudich & Watts) results in a highly purified protein with a molecular mass of 43,000 dalton. Summary Actin is a muscle protein localized in the I band of the myofibrils; acting along with myosin, it is responsible for contraction and relaxation of muscle. Each actin protomer binds one molecule of ATP and has one high affinity site for either calcium or magnesium ions, as well as several low affinity sites. Actin exists as a monomer in low salt concentrations, but filaments form rapidly as salt concentration rises, with the consequent hydrolysis of ATP. It occurs in globular (G-actin) and fibrous (F-actin) forms. Actin is found in all eukaryotic cells (except for nematode sperm). Actin is one of the most highly-conserved proteins, differing by no more than 20% in species as dive