Macrophage Colony-Stimulating Factor 1 (M-CSF) Human, His Tag, Sf9 Insect Cells Recombinant Protein

Description Macrophage Colony-Stimulating Factor 1 (M-CSF) Human, His Tag, Sf9 Insect Cells Recombinant Protein is a single, glycosylated polypeptide chain containing 231 amino acids (33-255 a.a.) and has a molecular mass of 26.1 kDa (molecular size on SDS-PAGE will appear at approximately 28-40 kDa). The M-CSF is expressed with an 8 amino acid His tag at C-Terminus and is purified by proprietary chromatographic techniques. Summary Macrophage colony-stimulating factor (M-CSF) is a cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development