ACIC CREAM 5%

International Name: ACYCLOVIR Pharmacological Group - Antiviral drugs for external use Manufacturer: Saluta Pharma Country: Germany Issuance form: Group III over-the-counter Pharmacological propertiesAcyclovir is an antiviral drug that is a synthetic analog of the nucleoside purine group. It is characterized by the inhibition of the human herpesvirus in vitro and in vivo, including the Herpes simplex (HSV) type 1 and 2 virus, it is active against Varicella zoster (VZV) and Epstein-Barr (RBV) viruses. In cell culture, acyclovir is characterized by well-expressed antiviral activity against HSV-1, -HSV-2, VZV, EBV and CMV viruses. Thymidine kinase of cells infected with HSV, VZV, and EBV viruses converts acyclovir into an acyclovir monophosphate-nucleoside analog, which is subsequently transformed into diphosphate and triphosphate by cell enzymes. Inclusion of acyclovir triphosphate in the viral DNA strand and subsequent cleavage of the strand causes blockade of viral DNA replicat