DHEA (Dehydroepiandrosterone) Powder Micronized

DHEA (Dehydroepiandrosterone) Powder Micronized

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REPRESENTATIVE DOCUMENTS COA *(Documents above may vary from batch received. Click here to request batch-specific documents) Supplement Facts & Directions Supplement Facts Serving Size: 100 milligrams Servings Per Container: Varies Amount Per Serving % Daily Value* DHEA (Dehydroepiandrosterone) 100mg † * Percent Daily Values are based on a 2,000 calorie diet.† Daily Value Not Established ‡ These supplement facts may vary from the product you receive.    Please call for exact numbers. Other Ingredients: None Contains: Free of:  Added Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives. Directions:  As a dietary supplement, start with 5 mg daily and increase to 100 mg over 1-2 week period as tolerated. An accurate gram weight scale is recommended. Warning: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS OR WOMEN. Consult a physician before using this product if you have, or have a family history of, prostate cancer, prostate enlargement, heart disease, low "good" cholesterol (HDL), or if you are using any other dietary supplement, prescription drug, or over-the-counter drug. Do not exceed the recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen. Discontinue use and call a physician immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms. Keep out of reach of children. Product Details Note: You must be at least 18 years of age to purchase this product. Due to state or federal law, we cannot ship this product to South Dakota, Missouri, Canada or Australia. Dehydroepiandrosterone (DHEA) is a steroid hormone, and it is one of the most prevalent steroids found in humans. Dehydroepiandrosterone concentrations peak between the ages of 20 and 30 and then sharply decline with age. The body synthesizes DHEA by converting dietary cholesterol into pregnenolone, a building block for numerous hormones. Via the CYP17 enzyme, pregnenolone converts into DHEA. The body produces dehydroepiandrosterone in the adrenal glands, testes, ovaries, and brain. However, most dehydroepiandrosterone synthesis occurs in the adrenals due to the amount of CYP17 enzymes expressed there. DHEA is a critical endogenous precursor to produce the sex hormones androgen, dihydrotestosterone (DHT), and estrogen. However, it performs several other biological functions by interacting with nuclear, cell surface, and neurotrophic factor receptors in the brain. Potential DHEA Benefits Low DHEA levels can have negative effects on heart health and emotional wellbeing. It also increases the risk of mortality. Keeping DHEA levels elevated isn’t only a concern for older adults either. By 30, DHEA levels begin to plummet. Over time, levels decrease by up to 80%. DHEA’s most potent effect is reducing several negative aspects of aging. Several studies conducted on men taking DHEA noted improvements in mood, heart health, hip bone density, joint health, and more. In women, DHEA supplements showed improvements in mood, menopause symptoms, sexuality, heart health, and bone density. Individuals with low DHEA often have lower bone density, making them more prone to bone fractures. Aging also diminishes bone density, so older adults may reap the most bone-related DHEA benefits. Some DHEA studies found the bone health benefits were particularly notable in older women. What Does Micronized Mean? The micronization process reduces the average size of DHEA particles. Micronized supplements are more bioavailable and easier to absorb. What Does 200 Mesh Mean? A mesh number describes the size of the screen supplement particles can pass through. The number of holes in a one-inch square screen determines the mesh size. PureBulk’s DHEA supplement passes through a 200 mesh screen. DHEA supplements may improve strength and exercise performance in certain individuals. Studies on older adults found DHEA improved their strength and physical functions. These improvements may help prevent falls and the associated bone fractures in the elderly. DHEA supplements may also enhance lean muscle mass in individuals with inhibited or impaired adrenal functions. DHEA supplements may improve fat mass by influencing food intake. Animal studies have shown that DHEA reduced how much food the subjects consumed with a notable reduction in fatty foods. In humans, DHEA supplements help improve feelings of satiety after eating. DHEA promotes heart health in a couple of ways. It helps protect blood vessel walls and maintains the overall health of blood vessels to improve vascular function. DHEA may help reduce lipoproteins in the bloodstream, as it uses cholesterol to create estrogen. DHEA may help regulate moods, as it enhances the production of beta-endorphins and other happiness hormones. The improvements to wellbeing are notable in the elderly and individuals with adrenal insufficiency. Potential DHEA Side Effects Most adults don’t experience side effects while taking DHEA supplements. However, due to DHEA’s interactions with hormones, DHEA supplements may cause minor effects like greasy skin, an increase in armpit hair growth, or acne. References https://pubmed.ncbi.nlm.nih.gov/16293766 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931814 https://www.ncbi.nlm.nih.gov/pubmed/3025870 https://www.ncbi.nlm.nih.gov/pubmed/20375886 https://www.ncbi.nlm.nih.gov/pubmed/21051590 https://pubmed.ncbi.nlm.nih.gov/16524719 https://pubmed.ncbi.nlm.nih.gov/16684650 https://pubmed.ncbi.nlm.nih.gov/11281367 https://pubmed.ncbi.nlm.nih.gov/15994348 https://www.ncbi.nlm.nih.gov/pubmed/15261843 https://www.ncbi.nlm.nih.gov/pubmed/25022952 https://www.ncbi.nlm.nih.gov/pubmed/6235241 https://www.ncbi.nlm.nih.gov/pubmed/12899651 https://www.ncbi.nlm.nih.gov/pubmed/28449564 https://www.ncbi.nlm.nih.gov/pubmed/24704256 https://www.ncbi.nlm.nih.gov/pubmed/11907709 https://www.ncbi.nlm.nih.gov/pubmed/10821876 https://www.ncbi.nlm.nih.gov/pubmed/19321570 https://www.ncbi.nlm.nih.gov/pubmed/18084691 https://pubmed.ncbi.nlm.nih.gov/20863330/ https://pubmed.ncbi.nlm.nih.gov/18000094/ https://pubmed.ncbi.nlm.nih.gov/15183694/ https://pubmed.ncbi.nlm.nih.gov/16487434/ http://atvb.ahajournals.org/content/20/3/782.abstract https://pubmed.ncbi.nlm.nih.gov/9526966/ https://www.ncbi.nlm.nih.gov/pubmed/11110996 https://www.ncbi.nlm.nih.gov/pubmed/11228759 https://www.ncbi.nlm.nih.gov/pubmed/11520945 https://www.ncbi.nlm.nih.gov/pubmed/21212768 https://www.ncbi.nlm.nih.gov/pubmed/15672938 https://www.ncbi.nlm.nih.gov/pubmed/14667889 https://www.ncbi.nlm.nih.gov/pubmed/15831289 https://www.ncbi.nlm.nih.gov/pubmed/11134123 https://www.ncbi.nlm.nih.gov/pubmed/10502590 http://jcem.endojournals.org/content/82/10/3498.abstract https://www.ncbi.nlm.nih.gov/pubmed/7515387 https://www.ncbi.nlm.nih.gov/pubmed/9876338 https://www.ncbi.nlm.nih.gov/pubmed/9024954 https://www.ncbi.nlm.nih.gov/pubmed/16735495 https://www.ncbi.nlm.nih.gov/pubmed/11940375 https://www.ncbi.nlm.nih.gov/pubmed/15356084 https://www.ncbi.nlm.nih.gov/pubmed/17050889 https://www.ncbi.nlm.nih.gov/pubmed/10760294 https://www.ncbi.nlm.nih.gov/pubmed/11975863 https://www.ncbi.nlm.nih.gov/pubmed/11109974 https://www.ncbi.nlm.nih.gov/pubmed/18632445 https://www.ncbi.nlm.nih.gov/pubmed/25022952 Tested by Accredited 3rd Party Labs PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here. *NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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