Biotinylated Human LILRA4/CD85g Protein, His-Avi Tag

LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades. Specifications Synonyms CD85g; ILT7; ILT-7; ILT7MGC129598; LILRA4; MGC129597 Uniprot No. P59901 Source Recombinant Biotinylated Human LILRA4/CD85g Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Glu24-Asn446. Molecular Weight The protein has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. Physical Appearance S