
3D Printed Hypertrophic Subaortic Stenosis
3D Printed Hypertrophic Subaortic Stenosis Clinical HistoryA thin 42-year-old American tourist was found dead in his hotel bedroom. A coroner’s autopsy was performed. PathologyThis is a longitudinal section through the heart displaying the left and right ventricles and interventricular septum. The outstanding abnormality is a grossly thickened interventricular septum and left ventricular hypertrophy. The aortic cusps that are visible appear unremarkable, as does the mitral valve. The ventricular septum is so large that it encroaches on the lumen of the left ventricle. DiagnosisIdiopathic hypertrophic subaortic stenosis, also known as hypertrophic cardiomyopathy. Further InformationSubaortic stenosis is considered to be acquired rather than congenital and is suggested to result from an underlying defect in the architecture of the left ventricular outflow tract (LVOT). The defect may be such that the resulting turbulent blood flow leads to progressive thickening