Alpha-1 Antitrypsin ELISA for Human Stool (ImmuChrom)

Description The ImmuChrom Alpha-1 Antitrypsin ELISA Kit is intended for the quantitative determination of alpha-1-antitrypsin (A1AT) in human stool or serum samples. Alpha-1-Antitrypsin is a 52 kD glycoprotein, which is produced by the liver, intestinal macrophages, monocytes and mucous membrane cells of the gut. It belongs to the group of acute phase proteins and is one of the most important proteinase inhibitor. Alpha-1-antitrypsin inhibits, beside others, the proteinases trypsin and the elastase of neutrophiles. A lack of α-1-AT leads to an enhanced proteolysis. Only a very small amount of alpha-1-antitrypsin is cleaved or resorbed in the gut. Therefore the measurement of α-1-AT in stool reflects the permeability of the gut during inflammatory processes. Type Sandwich ELISA, HRP-labelled antibody Other names A1AT ELISA, α-1-AT, SERPINA1, SERPIN A1, serum trypsin inhibitor, alpha 1 proteinase inhibitor, Alpha-1-antiproteinase, fecal Alpha-1-Antitrypsin, faecal Alpha-1-Antitrypsin Pri