Beta-Defensin 2 ELISA for Human Stool (ImmuChrom)

Description The Immuchrom Beta-Defensin 2 ELISA Kit is an immunoassay for the quantitative determination of ß-defensin 2 in human stool samples. For research use only. The group of Beta-defensins are a class of antimicrobial cationic arginine rich peptides and an integral part of the innate non-specific immune response. So far nine different ß-defensins are known in humans. This includes ß-defensin 2, which consists of 64 amino acids and has a molecular weight of 7 kDa. An intensified expression of ß-defensins take place through inflammation and micro-organisms. In Crohn's disease a deficiency of ß-defensin is observed. Due to the restricted barrier function of the intestinal mucosa, the inflammation typical for Crohn's disease can be caused by bacterial invasion. Applications inflammatory processes in the intestine integrity of the intestinal mucosa The ImmuChrom complete ß-defensin 2 kit allows an easy, rapid and precise quantitative determination of ß-defensin 2 in biological