Interleukin-2 (IL-2) Human, E. coli Recombinant Protein

Description Our bioactive Interleukin-2 (IL-2) Human, E. coli Recombinant Protein is a single, non-glycosylated polypeptide chain containing 133 amino acids and has a molecular mass of 15.4 kDa. The IL-2 is purified by proprietary chromatographic techniques. Summary IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. Other Names Interleukin 2, IL2, T-cell growth factor (TCGF), UniProtKB# P60568 Amino Acid Sequence APTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM