Lubricin Antibody, Native Bovine, 100 ug

Lubricin (PRG4) monoclonal antibody (mouse, clone 3A4) to detect the native form of bovine lubricin. Does not recognize reduced or denatured lubricin.   Lubricin is processed from the same gene as superficial zone protein, the proteoglycan 4 gene (PRG4). Lubricin is synthesized by synovial fibroblasts and secreted into the synovial fluid where its role is to regulate the lubrication of diarthrodial joints. Additionally, it is found in the meniscus, ligaments and tendons of our body. Mutations in the lubricin gene are associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome.Related Terms/Symbols PRG4 Proteoglycan 4 SZP Articular superficial zone protein Megakaryocyte stimulating factor Pericarditis syndrome Q92954   References/Citations: Wu, Y., Yang, Z., Denslin, V., Ren, X., Lee, C. S., Yap, F. L., & Lee, E. H. (2020). Repair of Osteochondral Defects With Predifferentiated Mesenchymal Stem Cells of Distinct Phenotypic Character Derived From a Nanotopographic Pla