T1/ST2 (IL-33R) Mouse, Monoclonal Antibody, FITC, 0.5 mL

Mouse T1/ST2 (IL-33 R) FITC conjugated monoclonal antibody (Clone: DJ8, Host / Isotype Subclass: Rat IgG1, light chain not isotyped) for the identification and purification of murine T helper 2 (Th2) cells and all forms of murine mast cells. T1/ST2 (also known as IL-1 R4 or IL-33Ra) is a transmembrane glycoprotein expressed on mast cells and Th2 cells. It is a selective marker for both murine and human Th2 lymphocytes and plays a role in regulating inflammatory responses. IL-33 is a recently identified member of the IL-1 family of cytokines and is involved in Th2 mediated immune responses. IL-33 mediates its biological effects via T1/ST2 binding. The roles of IL-33 and T1/ST2 (IL-33Ra) have been investigated in many immune responses such as allergy, asthma, rheumatoid arthritis and osteoarthritis. References/Citations: Prince, N., Peralta Marzal, L. N., Roussin, L., Monnoye, M., Philippe, C., Maximin, E., ... & Perez-Pardo, P. (2025). Mouse strain-specific responses along the gut